Paradigm shift in pharmacological treatment of periodontitis

Fat Grafting Technique, A Paradigm Shift in the Treatment of Tuberous Breast

BACKGROUND The tuberous breast syndrome is a condition that affects young women and can bring on serious disorders of self-esteem. There are numerous surgical techniques to correct this condition, but most of them include the use of breast implants to replace lack of volume. Nowadays, patients are increasingly becoming more demanding to get a definitive solution with minimal aesthetic sequelae...

Paradigm-HF: a Paradigm Shift in Heart Failure Treatment?

DOI: 10.5935/abc.20160009 In the first semester of this year, the U.S. Food and Drug Administration (FDA) approved a new drug for the treatment of heart failure, LCZ696, commercially known as Entresto. This new treatment option was evaluated by the FDA on a priority basis (fast track designation), which allowed a faster release than usual. In Brazil, the drug is being evaluated by the National ...

Paradigm Shift

A paradigm shift, suggested by Thomas Kuhn [1], is not just a small change in science, or the modification of a theory. It is a scientific revolution and completely changes the way in which science looks at the world. It often dictates how the public looks at the world. For example, Darwin's theories [2] were intensely debated by scientists and theologians. This debate spilled over into the pub...

paradigm shift of health towards obesity in childhood

The Paradigm Shift to Non-Treatment of Asymptomatic Bacteriuria

Asymptomatic bacteriuria, also called asymptomatic urinary infection, is a common finding in healthy women, and in women and men with abnormalities of the genitourinary tract. The characterization and introduction of the quantitative urine culture in the 1950s first allowed the reliable recognition of asymptomatic bacteriuria. The observations that a substantial proportion of patients with chro...